- October 9, Syrian Democratic Forces reportedly continued their advance in the eastern Deir-Ez-Zor governorate, capturing Mweileh town in Sur subdistrict, located north of Sur city.
- October 10, Syrian Regime offensive is largely dependent on Russian aerial coverage; the Russian Foreign Ministry announced that 150 daily Russian airstrikes had targeted ISIS bases in Mayadin city.
- October 15, SDF spokesperson announced that all willing combatants have evacuated the city; however, the likely destination of potential ISIS-affiliated evacuees is currently unknown. Furthermore, the SDF-led ‘Wrath of Euphrates’ operation against ISIS has led to SDF control over most neighborhoods in Ar-Raqqa city amidst heavy aerial support by the U.S.-led coalition, resulting in a high rate of civilian displacement.
- October 15, Syrian Regime forces and Allied Militias, supported by Russian aerial and ground forces, continued their advance south of Deir-Ez-Zor city, Syrian Regime forces, advanced into Al Mayadin city, Al Mayadin subdistrict, located 43.8 km south of Deir-Ez-Zor city.
- October 17, About 400 Islamic State (ISIS) members, including foreign fighters, have in recent weeks surrendered to U.S. backed forces in ISIS former Syrian stronghold Raqqa; inside source confirmed that the ISIS Syrian fighters were transferred to "Ayn Issa" Camp, while the foreign fighters were transferred to "Suluk" Military headquarter.
- October 18, Syrian Democratic Forces reportedly captured the several villages from ISIS, 7 KM eastern side of Deir-Ez-Zor City.
Important Note: As of the end of September, nearly 708,000 individuals are reported to still remain in ISIS-held communities in Deir-Ez-Zor governorate. This includes approximately 120,000 individuals in ISIS-held northern Deir-Ez-Zor governorate between Tabni, Tabni subdistrict, Deir-Ez-Zor City and the Euphrates River; 68,000 individuals in the ISIS-controlled western Deir-Ez-Zor governorate from Khasham in Khasham subdistrict to Markada across Khabour River; 120,000 in southern Deir-Ez-Zor governorate from Hajin to Abukamal; and nearly 400,000 individuals in the central Deir-Ez-Zor governorate.